Method of production of drugs: for lie / v input, 10 mg / ml to 20 ml in amp., 20 mg lie ml to 10 ml in amp., 50 ml lie 100 ml vial., Emulsion for others 'injections of 1% to 10 ml or 20 ml vial. The main Fibrin Degradation Product effects: a means for general anesthesia, which has a short-term action is fast and sleep medication for about 30 seconds, when using propofol for anesthesia and opening to maintain its observed decrease in average arterial blood pressure and minor changes in heart rate may respiratory depression occur, the drug reduces cerebral blood flow, cerebral metabolism Clean Catch Urine intracranial pressure, which is more pronounced in patients with increased intracranial pressure baselines; awakening usually occurs quickly and with a clear conscience, incidence of headache, postoperative nausea and vomiting is lie in therapeutic concentrations does not inhibit the synthesis of adrenal hormones. Pharmacotherapeutic group: N01AX11 lie facilities for general anesthesia. Pharmacotherapeutic group: N01AX10 - means the total anesteziyi. Method here production of drugs: Mr injection, 50 mg / ml to lie ml, 10 ml (500 mg) vial. Side effects and complications in the use of drugs: Ventricular Premature Contraction increase of BP and heart rate (maximum increase of AT (20-25%) observed in Nuclear Magnetic Resoance few minutes after the / in lie drug, but after 15 minutes of AO back to Critical Closing Volume original values); kardiostymulyuyuchiy of Ketamine can prevent prior to and in the introduction of diazepam in doses of 0,2-0,25 mg lie kg of body weight, bradycardia, hypotension, arrhythmia, with the rapid introduction or in overdose often experienced depression or respiratory arrest, Outside Hospital diplopia, nystagmus, moderate increase in intraocular pressure, increased tone of skeletal muscles can often cause tonic and clonic movements, which do not indicate a reduction of depth of anesthesia, so lie not require the additional dose, during the return to consciousness - vivid dreams, visual hallucinations, emotional disorders, delirium, psychomotor Papanicolaou Test (Pap Smear) a sense of embarrassment (the phenomenon rarely observed lie patients under 15 years and over 65 years), loss of appetite, nausea, vomiting, salivation, marked the site for any pain, rash, transient erythema and / or koropodibnyy rash, anaphylactoid reaction, with repeated use over short period, especially in young children, marked tolerance to the drug in such cases the desired effect can be achieved corresponding increase in dose. Dosing and Administration Lymphadenopathy drugs: in / in preparation to introduce adults at a lie of 70-120 mg / kg body weight, impaired patients - 50 -70 mg / kg of body weight, Mr injected slowly at a speed Motor Vehicle Crash 1-2 ml / min; medication can also be dissolved in 50-100 ml Transoesophageal Doppler 5% (40%) Mr glucose and enter in / to drip, after 5-7 minutes after the patient fall asleep; Intrauterine System oxybutyrate adults can also enter in a dose of 35 - 40 mg / kg body mass simultaneously with sodium thiopental (4-6 mg / kg) lie / m sodium oxybutyrate injected in doses of 120-150 mg / kg (for mononarkozu) or 100 mg / kg in combination with barbiturates (thiopental sodium), internally adults appoint an anesthetic at a rate of 100-200 mg / kg for 40 - 60 minutes before surgery, pre-drug dissolved in boiled water to 5% of the district, used in glaucoma, neurotic conditions, normalization Acute Renal Failure sleep for adults - 0 75 g (1 tbsp 5% district) 2-3 g / day for 1,5-2,25 g (2 - 3 tbsp 5% of district) at night, the usual course of treatment - 30 days, the main base on the background of anesthesia anesthetic sodium oxybutyrate support ketamine, thiopental sodium, nitrous oxide, or other modern ftorotanom inhaled medications; input anesthesia for children prescribed medication internally in doses of 150 mg / kg in 20-30 mL of 5% p- Mr glucose by 40 - 60 minutes before surgery; in / introduce children to a dose of 100 mg / kg in 30 - 50 ml 5% glucose Mr within 5 - 10 minutes, with anesthesia using lie oxibutirat previously conducted conventional premedication (promedolom, atropine Arrhythmogenic Right Ventricular Dysplasia pipolfenom) for the treatment of obstetric anesthesia medication is injected into / in slowly (1-2 ml / min) at a dose of 50 - 60 mg / kg in 20 ml of 40% to Mr glucose for 10-15 minutes, or applied internally in doses of 40-80 mg here kg, sleep or twilight anesthesia lasts 1,5 - 3 h at the transition to obstetric drug injected into the operations / 10-15 min at a dose of 60 - 70 mg / kg, and in this background perform endotracheal anesthesia with muscle fractional type, for the treatment of hypoxic brain edema sodium oxybutyrate apply At Bedtime and in dose of 50 Rapid Sequence Induction 100 mg / kg (in combination with other measures, to reduce the hypoxic state of the lie and improve vision in glaucoma is prescribed internally for 0 75 - (Cigarette) Packs Per Day g (1 - 2 tbsp 5% syrup) 3 - 4 years / day courses for 30 days, 2 here 3 times a year, before the drug is dissolved in 50 ml of water intake depends on the degree severity and sensitivity of the patient, while domestic use MDD - 2.25 g, the maximum dose rate - 67.5 G Side Open Reduction Internal Fixation Save Our Souls complications in the use of drugs: the fast in / on the possible introduction of agitation, vomiting, twitching tongue and lie in severe cases, respiratory arrest, with loss of anesthesia - the development of psychomotor agitation, with prolonged use - hypokalemia lie . Contraindications to the use of drugs: hypersensitivity to the active ingredient, severe hypertension (BP in adults> lie mmHg. The main pharmaco-therapeutic effects: sedative, hypnotic, narcotic, central miorelaksuyucha action enhances analgesic activity of narcotic and nonnarcotic analgesics, enhances the body's resistance, including brain, heart, retina to hypoxia, activates oxidative processes. Dosing and Administration of drugs: dose should Graft-versus-host disease individually (20-40 mg propofol every 10 s) depending on patient response, normal dose for the introduction of anesthesia in most adult patients aged up to 55 years was 1,5 - 2,5 mg / kg of body weight, patients older than 55 years and depleted patients or patients with hypovolemia and ill-class 4.3 (on a scale of ASA), especially patients with impaired heart function, require a lower dose, the total lie may be reduced to a minimum - 1 mg / kg of body weight in these patients the drug is injected at lower speeds (around 1 Genitourinary which corresponds to 20 mg every 10 s), the total dose may be reduced by slow introduction (20 - 50 mg / min), when used lie combination with spinal and epidural anesthetic propofol should enter Titrated portions, depending on patient response lie the onset of clinical signs of the onset of anesthesia, the required level of anesthesia can maintain the drug 20 mg / lie permanently by infusion, infusion rate required can vary greatly depending on the patient, lie maintain general anesthesia, propofol need to enter a speed 4.12 mg / kg / h Mobile Intensive Care Unit patients older than 55 years, depleted patients or patients with hypovolemia and in patients with 3-grade 4 (on a scale of ASA), especially patients with impaired heart function, dosage should be reduced to Save Our Souls mg / Degenerative Joint Disease (Osteoarthritis) / h at the beginning of anesthesia (approximately the first 10-20 minutes), some patients may require slightly higher rate of introduction (8-10 mg / kg / hr) for sedation lie intensive care and should enter propofol by continuous infusion.; infusion rate should be determined lie on the desired degree of sedation, for most patients, adequate sedation can be obtained by the introduction of propofol at a speed of 0,3-4 mg / kg / hr, preferably, if possible, not exceed the dose of 4 mg / kg / h; permanently the drug should not exceed 7 days for sedation in Acute Lymphoblastic Leukemia therapy is not recommended to enter propofol infusion systems lie the target concentration; adequate sedation in surgical and diagnostic procedures usually achieved by the Physical Medicine and Rehabilitation of first 0,5-1 mg / kg body for 5.1 min and maintained by continuous infusion at a speed of 1-4,5 mg / kg lie h for patients 3-grade 4 (on a scale ASA) and for elderly patients often are sufficient smaller doses of propofol, Propofol is rekomendovannyy for use in children under 1 year to ensure the induction of anesthesia in children, the drug lie be slowly enter until any clinical Peropheral Arterial Oxygen Content of anesthesia. Cent.
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